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r-HBvax is a non -infectious, inactivated recombinant subunit viral vaccine derived from HBsAg produced in yeast cells using recombinant DNA technology developed by Korea GreenCross Corporation. It is a whitish turbid liquid which is produced by culture of genetically engineered yeast cells which carry by several physico-chemical steps such as ultra centrifugation, column chromatography and formaldehyde treatment.
Japanese Encephalitis Vaccine is produced by VABIOTECH upon technology transfer from BIKEN INSTITUTE-JAPAN. This is an inactivated, purified vaccine derived from mouse brain. The quality of product meets the WHO's and Japan's minimum requirements for Japanese Encephalitis Vaccine with high safety, potency and efficacy.
Oral Cholera vaccine is produced from Cholera bacteria, consists of V.Cholera Classical biotype, El Tor and O 139. The whole cell components of vaccine are inactivated by formaldehyde or heat. These components include toxin coregulated pilus (TCP).
HEPATITIS A VACCINE (Havax®)
Havax®, hepatitis A vaccine is a suspension containing inactivated hepatitis A virus (HM 175 hepatitis A strain) absorbed onto aluminum hydroxide.
The virus is propagated in primary key monkey kidney cells of Maccaca mulatta. A virus suspension is obtained by cell lysis following by purification and ultra- filtration steps. Inactivation of the virus assured by treatment with formalin.
Havax® meets the World Health Organization minimum requirements for biological substances. The viral antigen content is determined by an ELISA technique.
WIPO Prize 2003
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